The result will have felt more significant since it came at the very ground where the Australians lost the Ashes series earlier this summer - Clarke scored 187 on that occasion - and with three matches left in the series. Clarke's knock, which was the first ODI hundred recorded by an Australian on English soil, would be supplemented by George Bailey (82) during a fourth-wicket stand of 155 in a total of 315 for seven.
It left the hosts with a formidable chase and they duly succumbed, despite half-centuries from Kevin Pietersen (60), captain Eoin Morgan (54) and Jos Buttler (75). England were eventually bowled out with the final 5.4 overs unused.
Chief among Australian bowlers was Mitchell Johnson, with Michael Caberry and Jonathan Trott put out for scores of just four and nought respectively. The latter was caught out - and caught behind - after Johnson delivered a delicious short ball which nicked the shoulder of the bat Joe Root could come through Johnson's new-ball spell, but only to then be through the gate on the back foot by James Faulkner.
Kevin Pietersen sounded a brief charge with five 4s and two 6s to reach 50 but he would succumb to a tame catch after Johnson returned to the wicket. Morgan then went in the first over of the batting powerplay when the Irishman mistimed the returning Clint McKay (three for 47) to extra-cover, leaving his side to fall behind in the series.