Scotland's David Millar is in the line up for Garmin-Sharp in Tuscany, while this year's Tour de France winner Chris Froome and Geraint Thomas are among Team Sky's six-man squad.
In the women's race, Britain's Joanna Rowsell and Dani King look likely to ride for Wiggle Honda, with Olympic silver medallist Lizzie Armitstead and Emma Trott named for Boels-Dolmans.
Sir Bradley Wiggins, fresh from the Tour of Britain, will contest the men's individual time-trial alongside compatriot Alex Dowsett on Wednesday, while Froome will also be challenging for the road race title a week today, backed by Wiggins, Mark Cavendish, Steve Cummings, Josh Edmondson, Ian Stannard, Jonathan Tiernan-Locke and Thomas.
In the women's road race on Saturday, Armitstead will be joined by junior world champion Lucy Garner, making her senior debut, alongside Katie Colclough and Nikki Harris.
The 2013 British National Track Championships also begin this week with a strong Scottish contingent heading down to Manchester. The five-day event will provide an opportunity for many to gain the qualification standard ahead of the 2014 Commonwealth Games.
Confirmed on the start-list are Charline Joiner, Katie Archibald, Emma Baird, Louise Haston, Eileen Roe, Louise Borthwick and Jennifer Davis, while Callum Skinner, John Paul, Evan Oliphant, James McCallum and Silas Goldsworthy will also compete.
They will face a clutch of Olympic gold medallists including English riders Ed Clancy, Jason Kenny, Laura Trott, King and Rowsell.
The latter trio will be the ones to beat when Elinor Barker of Wales joins them in the women's team pursuit as the event is contested by teams of four riders over 4000m for the first time.