Injury and illness have forced Northampton back-row men Pat Lam and Budge Pountney out of today's fourth-round Tetley's Bitter Cup trip to Sale.
Lam, who scored a hat trick of tries at Sale last Saturday, has been playing with a broken hand for some time, while Pountney is ill.
Lock Jason Chandler and youngster Simon Hepher have been drafted into the squad.
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