The Scottish Government has ordered a review after two families whose babies died during childbirth at the same hospital spoke out about their experiences.
Both families believe mistakes were made at Crosshouse Hospital in Kilmarnock, East Ayrshire, and they have called for a public inquiry into the deaths, BBC Scotland reported.
NHS Ayrshire and Arran has apologised for any "failings they experienced during their time with us".
Between 2008 and March 31 this year, there were four Significant Adverse Event Reviews concerning stillbirth deaths at Ayrshire Maternity Unit at the hospital, the health board said. The BBC said there have been six so-called "unnecessary" deaths of babies at the hospital since 2008.
Health Secretary Shona Robison has now instructed Healthcare Improvement Scotland (HIS) to carry out a review into the cases in Ayrshire and Arran "to inform me whether the correct procedures and processes were properly followed" in these instances.
She said: "I have asked HIS to report back to me with their findings at the earliest opportunity, after which, I would be happy to discuss those findings with the families concerned.
"If there are lessons to be learned or improvements which need to be made, we will not hesitate to act."
She also said: "At the heart of any incident is a family that is suffering from pain or loss, which is why we must do everything we can to mitigate against similar incidents happening again."
A Scottish Government spokesman confirmed the scope of the review.
"HIS are being asked to review the handling of adverse events within maternity, including the six cases highlighted," he said.
"It will be for HIS to determine how it will proceed with its review to meet the aims set out by the Health Secretary."
June and Fraser Morton's son Lucas died at Crosshouse last November.
Mr Morton told the BBC: ''Everything that could have gone wrong, went wrong. I believe they were understaffed and overworked. They didn't have the training knowledge and experience, and I believe that comes back to management issues.
"If mistakes had not been made, the difference is quite simple. Lucas would have been here. It would have been his first birthday. The independent reports substantiate that and say earlier intervention would have led to a different result."
Denise and Steven Campbell's son Joseph died during childbirth at the same hospital four years ago.
Mrs Campbell told the broadcaster: ''Our side of the story never, ever got asked. They said they just sat round the table with a cup of tea and talked about it and decided there was nothing that could have been done - that it was just one of these things.
''Then we spoke to the consultant who said things should have been done differently - especially in relation to monitoring Joseph's heartbeat.''
The health board said it takes the matters seriously and is engaged with both families.
Dr Alison Graham, executive medical director, said: "I would take this opportunity again to apologise to both families for any failings they experienced during their time with us.
"NHS Ayrshire and Arran is committed to ensuring that if there is any possibility that there has been avoidable harm, this is investigated thoroughly and that we are open, honest and transparent about this.
"When reviews identify that there has been avoidable harm we speak with people affected and report this openly through our clinical governance systems."
She added: "Since 2008 up until March 31 2016, there have been four Significant Adverse Event Reviews concerning stillbirth deaths at Ayrshire Maternity Unit. During this time, 33,716 babies have been born at Ayrshire Maternity Unit."
Lucas's death has been reported to the Crown Office, which is investigating.
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