Building muscle can give you the results you're looking for, whether you want to feel more confident or simply improve your health and fitness. There are many ways to achieve this goal, but supplementation is one of the most effective.
The right supplements can help stimulate muscle growth and enhance your workouts. But with so many fake supplements being advertised online, how can you find the right one? To make it easy for you, we've compiled a list of top-rated muscle-building supplements, with PrimeShred taking the #1 spot.
Best Supplements for Muscle Growth in 2025: Quick Summary
- PrimeShred - Best supplement for muscle growth overall
- Testogen - Best for fast results
- D-Bal Max - Best for bodybuilders
- TestoPrime - Best testosterone booster for muscle growth
- CrazyBulk Ultimate Stack - Best muscle-growth stack
- Tren-Max - Best for all-around conditioning
- Anadrole - Best for strength and stamina
- Deca-Max - Best for endurance
Types of Supplements for Muscle Growth
There are five main types of dietary supplements to gain muscle. Each type has its benefits and can help you achieve your goals differently:
- Testosterone boosters
- Pre-workout supplements
- Post-workout supplements
- HGH supplements
- Mass gainers
Testosterone Boosters
Natural testosterone boosters aim to support your body's production of this vital hormone, potentially leading to increased strength, improved recovery, and enhanced muscle growth. They often include ingredients like D-aspartic acid, zinc, and ashwagandha.
Pre-Workout Supplements
Pre-workout supplements for muscle growth can help you get the most out of your workouts. They can increase energy levels, improve stamina, and enhance focus and mental clarity. This can help you work out harder and for more extended periods, leading to increased muscle growth.
Many pre-workouts include creatine and collagen for further support in this area. Creatine for muscle growth can significantly boost your ability to produce energy rapidly during intense exercise like weightlifting.
Post-Workout Supplements
Post-workout supplements for muscle repair are designed to kickstart the recovery process after intense exercise. They aim to rapidly replenish nutrients used during training and facilitate muscle repair and growth.
Typically, these muscle recovery supplements feature fast-digesting protein sources to deliver essential amino acids to the worked tissues quickly, initiating muscle protein synthesis. Post-workout supplements also leverage ingredients like BCAAs and HMB for muscle recovery and to help reduce muscle breakdown.
HGH Supplements
Human growth hormone (HGH) plays a role in muscle growth and repair, and some of the best bodybuilding supplements claim to boost its release. While they don't directly inject HGH (which is illegal without a prescription), they aim to support the body's natural HGH production for increased muscle mass and strength.
Mass Gainers
If you're a "hard gainer" struggling to pack on pounds, mass gainers are your calorie-dense allies. These supplements are loaded with protein, carbohydrates, and often fats, providing a convenient way to meet your calorie surplus needs for muscle growth.
Remember to use mass gainers strategically, though, as their high-calorie count can also contribute to fat gain if not balanced with your overall diet and activity level.
Best Supplements for Muscle Growth Reviewed and Compared for 2025
Some natural supplements can help you maximize your gains with a rigorous exercise routine and a protein-filled diet. To reach your fitness goals faster and more effectively, understanding your options and choosing the right supplement can go a long way. Here are our best supplements for muscle growth, including the top ones in each category.
1. PrimeShred - Best Supplement for Muscle Growth Overall
Pros
- Soy, gluten, and dairy free
- Suitable for vegans and vegetarians
- 100-day money-back guarantee
- Subscribe and save 20% +3 gifts
Cons
- Contains stimulants
Who Should Try PrimeShred?
Do you have a few extra pounds to lose and want to tone up your physique? PrimeShred can help. The supplement's thermogenic properties help to increase energy levels and metabolism, while the fat-burning ingredients support decreased body weight.
Who Shouldn't Take PrimeShred?
PrimeShred contains stimulants like caffeine, so it is not recommended for those sensitive to stimulants or those with anxiety disorders.
Cost
- 1-month supply: $59.99 or $47.99 for subscribers
Feedback From Users
PrimeShred holds an average rating of 3.6/5 based on 28 reviews on Amazon. One user described a positive experience, noting a "slight decrease in appetite" and a "noticeable increase in energy & focus." However, Joseph, who gave the product two stars, expressed two criticisms: a desire for a single-pill dosage and a lack of appetite suppression [1] [2].
2. Testogen - Best for Fast Results
Pros
- Free worldwide shipping on all orders
- Save up to 40% when you subscribe for 3 months or longer
- 100-day money-back guarantee
- Free diet and exercise program when you join the community
Cons
- No key multivitamins for extra muscle growth and repair
Who Should Try Testogen?
For those seeking a supplement that helps boost energy, mood, focus, and vitality, Testogen may be a suitable option. The manufacturer claims results within two weeks, with muscle and strength gains possible within a month when combined with regular training. This is plausible, given the inclusion of proven T-boosters like zinc, tribulus, and tongkat ali, though individual results can vary.
Who Shouldn't Take Testogen?
If you have heart issues, hormone-sensitive conditions like prostate or breast cancer, or diabetes, it's best to try other top supplements for muscle gain or consult a doctor. Testogen includes ingredients that can interact with heart medications (like hawthorn) and may potentially influence hormones (tribulus, epimedium, and saw palmetto).
Cost
- 1-month supply: $54.99 or $43.99 when you subscribe
Feedback From Users
While one Amazon reviewer, a 72-year-old, described a significant increase in energy, enabling them to "run up the stairs like a kid on Christmas morning,” another user expressed dissatisfaction, stating that the product "did not work at all [3] [4]."
3. D-Bal Max - Best for Bodybuilders
Pros
- Try it risk-free for 2 whole months
- Suitable for vegetarians
- Save up to 20% with frequent flash sales
- Pay in installments for bulk orders
Cons
- It might be too stimulating for those who are caffeine-sensitive
Who Should Try D-Bal Max?
D-Bal Max is an excellent option for those looking for an all-natural way to improve their gym results. It's also ideal for those looking for a performance enhancer, as it can help you achieve bigger, better gains.
Who Shouldn't Take D-Bal Max?
Although one of the best supplements for muscle growth, D-Bal Max includes 200 mg of caffeine, which might cause side effects like jitters, eye twitching, or increased heart rate. Those who are sensitive to stimulants should consider stimulant-free alternatives.
Cost
- 1-month supply: $69.99
- 3-month supply: $139.99
- 5-month supply: $209.99
Feedback From Users
Although the official website showcases several positive reviews for D-Bal Max, exploring Reddit or Quora may provide a more comprehensive view of customer experiences.
4. TestoPrime - Best Testosterone Booster for Muscle Growth
Pros
- Recommended by 418 clinicians on FrontrowMD
- 60-day refund policy
- Manufactured in FDA-approved facilities
- Subscribe and save 15%
Cons
- Some users find the garlic odor unpleasant
Who Should Try TestoPrime?
If you're hitting the gym regularly but need that extra edge to build lean mass more, overcome plateaus, or counteract age-related declines in energy and recovery, TestoPrime could be beneficial. Its blend of ingredients aims to support natural testosterone production, which is crucial for muscle synthesis, increased strength, reduced stress, and boosted energy levels.
Who Shouldn't Take TestoPrime?
Avoid TestoPrime or talk to your doctor first if you're taking regular medication like blood thinners, thyroid medication, blood pressure drugs, or sedatives. Those with known allergies to ashwagandha, garlic, or pomegranate should also use caution.
Cost
- 1-month supply: $59.49
- 3-month supply: $118.99
- 5-month supply: $178.49
Feedback From Users
Trustpilot reviewer Jonathan rated the supplement five stars. He states that TestoPrime is effective, though it requires him to eat breakfast more often, which he attributes to its energy-boosting effects [5].
However, Ayman reports a negative experience, having received a bulk order of six bottles with a short expiration window (10 months or less). He was also unhappy with the unresolved customer support issues [6].
5. CrazyBulk Ultimate Stack - Best Muscle-Growth Stack
Pros
- Subscribe and save 35%
- Delivery within 24-48 hours
- Free shipping
- No needles or prescriptions needed
Cons
- The dosage might overwhelm some people
Who Should Try CrazyBulk Ultimate Stack?
Are you serious about transforming your physique and pushing your limits in the gym? The CrazyBulk Ultimate Stack is designed for dedicated individuals – bodybuilders, athletes, or anyone committed to achieving significant muscle gains, explosive strength, rapid fat loss, and peak performance.
Who Shouldn't Take CrazyBulk Ultimate Stack?
This stack contains gelatin, so it is not suitable for vegans. Additionally, managing six different muscle growth supplements daily requires serious commitment. Plus, the sheer number of pills involved can feel quite overwhelming for some users to stick with consistently.
Cost
- 1-month supply: $349.99
Feedback From Users
On Trustpilot, Jason praised the appealing stack offers, which simplified his ordering decision and were boosted by a "buy 2 get 1" promotion. He also commended the easy checkout and swift shipping, expressing overall satisfaction with the product and experience. However, Sam's Trustpilot review detailed a negative customer service encounter [7] [8].
6. Tren-Max - Best for All-Round Conditioning
Pros
- 60-day money-back guarantee
- Buy 2, get 1 free
- Free training and nutrition e-guides with every order
- Frequent discount codes at checkout
Cons
- Free shipping only for orders over $100
Who Should Try Tren-Max?
Choose Tren-Max if you aim for the ultimate edge in all-around conditioning and seek to simultaneously sculpt lean muscle, torch stubborn fat, and unleash more stamina and strength.
Who Shouldn't Take Tren-Max?
Tren-Max is one of the best supplements for muscle growth if you’re undergoing intense training, so it's generally unsuitable for casual users.
Cost
- 1-month supply: $64.99
- 2-month supply + 1 free: $129.98
Feedback From Users
On Trustpilot, Edward praised the supplements, reporting feeling great and improved focus after taking Tren-Max and Testo-Max. In contrast, John expressed disappointment, noting no noticeable effects [9] [10].
7. Anadrole - Best for Strength and Stamina
Pros
- Huge savings with bulk orders
- Freebies worth $97 with every order
- Save up to 20%
- 60-day money-back guarantee
Cons
- Not suitable for vegans
Who Should Try Anadrole?
CrazyBulk Anadrole might be right up your alley if you want to enhance your strength and stamina during intense training sessions. As one of the top supplements for strength and muscle mass, it features a blend including iron and B vitamins crucial for oxygen transport and fighting fatigue.
You also get beetroot (known for enhancing blood flow), L-carnitine for energy production, and the adaptogenic shilajit, famed for boosting vitality.
Who Shouldn't Take Anadrole?
Those with liver or kidney issues, iron overload disorders, blood clotting problems, or those taking blood thinners or blood pressure drugs should consult a doctor first. While Anadrole is among the best supplements for muscle gain and strength for many people, it contains gelatin, making it unsuitable for vegans.
Cost
- 1-month supply: $64.99
- 2-month supply + 1 free: $129.98
Feedback From Users
While Ramiro's five-star Trustpilot review celebrated Anadrole's rapid delivery and positive impact on lifting, Jeff raised another issue. He reported receiving a different product than he ordered [11] [12].
8. Deca-Max - Best for Endurance
Pros
- Save over $100 with the buy-2-get-1-free offer
- Enjoy a 60-day, risk-free trial
- Straightforward formula
- Discreet packaging
Cons
- Lacks key vitamins and minerals
Who Should Try Deca-Max?
Deca-Max is among the best supplements for muscle growth if you want more from your workouts. The supplement's ability to increase endurance and provide joint pain relief can help you push your limits in the gym for more effective bulking.
Who Shouldn't Take Deca-Max?
Deca-Max contains shellfish and may not be suitable for those who are allergic. It also includes ginseng, arginine, and tribulus, which can potentially interact with blood thinners, blood pressure drugs, or diabetes medication (or affect blood sugar levels).
Cost
- 1-month supply: $64.99
- 2-month supply + 1 free: $129.98
Feedback From Users
Although Jason gave Deca-Max a five-star rating on Trustpilot, citing consistently excellent orders, he reported an issue with one shipment that included several broken capsules in an otherwise intact bottle [13].
Conversely, Jimmy's Trustpilot review expressed a different concern, stating that the product descriptions were "redundant" and that the product's efficacy remained to be determined after two weeks of use [14].
How To Choose the Best Supplements for Muscle Growth
When comparing different best workout supplements, we evaluated them on the following criteria:
Clean and Natural Ingredients
Natural ingredients have less risk of side effects and are generally well-tolerated. This means no artificial colors, flavors, sweeteners, or fillers.
Non-GMO
Non-GMO supplements are not made with genetically modified ingredients. They are generally considered to be well-tolerated and more natural, and they are less likely to contain harmful chemicals or pesticides.
Solid Refund Policies
A good refund policy shows that a company stands behind its products and is confident in their quality. This gives you peace of mind that you can get your money back if you're unhappy with the results.
Bulk Discounts
Bulk discounts are an excellent way to save money on the best supplements for muscle growth. They're also a good indicator that a company is confident in its product and is willing to sell it at a lower price per serving.
>>Buy PrimeShred here
Potential Side Effects of Supplements for Muscle Growth
While the best supplements for muscle growth can be beneficial for bulking, some can cause adverse effects, including:
- Gastrointestinal issues
- High blood pressure
- Kidney damage
- Liver damage
- Cardiovascular issues
Tips To Follow When Using Supplements for Muscle Growth
In addition to muscle-building supplements, there are other things you can do to increase muscle growth. These tips can help you get the most out of your training and nutrition program:
Regular Weight Training and Exercise
To build muscle, you need to exercise regularly. Weight and resistance training are the best exercises for increasing lean body mass. Rest days are also just as important as training days. Overtraining can hinder progress and increase injury risk. Allow your muscles time to recover and rebuild.
Follow a Strict Diet
To build muscle, you need to eat a diet high in protein. This diet will help your body recover from your workouts and promote muscle growth. Adding any of the best supplements for lean muscle to your routine can provide targeted nutritional support to help maximize results.
Manage Stress
Stress can cause your body to release cortisol, leading to muscle breakdown. Incorporate stress-reducing activities into your routine. This could be meditation, deep breathing exercises, yoga, spending time in nature, or simply listening to calming music.
Get Enough Sleep
Sleep is essential for muscle growth. During sleep, your body releases hormones that promote muscle growth and repair. Most adults need 7-9 hours of sleep daily for optimal recovery and performance.
FAQs on Best Supplements for Muscle Growth
Now that we've reviewed some of the best muscle-building supplements, let's answer some common questions about these products and how they influence muscle development.
What Is the Best Supplement for Muscle Gain?
Based on our guide, PrimeShred takes the crown among the best natural supplements for muscle growth we reviewed.
Which Supplement Is Best for Muscle Gain and Fat Loss?
The CrazyBulk Ultimate Stack offers the best supplements for muscle growth and fat loss.
Do Protein Supplements Effectively Support Muscle Building?
Your muscles are made of protein and need protein to repair and grow after workouts. Consuming enough protein is essential for building muscle mass.
There are different protein supplements, but the best sources for muscle growth are whey protein isolate and casein protein. These protein powders are easily digested and give your muscles the amino acids they need to repair and grow.
What Are the Best Supplements for Muscle Growth for Women?
Your absolute go-tos should be a high-quality protein powder. It could be whey, casein, or plant-based options like soy or pea. Creatine supplements are also incredibly well-researched, well-tolerated by women, and fantastic for boosting strength, workout performance, and muscle gain.
While other supplements like pre-workouts can help with gym energy, nailing your protein intake, and considering creatine are the most impactful supplement strategies to support your hard work in the gym.
What Are the Best Supplements for Building Muscle Over 40?
Building muscle effectively after 40 often means focusing on smart recovery and consistent effort, and the right supplements can undoubtedly lend support. While individual needs vary, the most reliable staples (as mentioned) remain creatine, casein, whey, or plant blends.
Additionally, consider vitamin D supplementation, as deficiency is common and impacts muscle function. Omega-3 fatty acids (fish oil) can help manage inflammation, potentially aiding recovery and joint health, which are often prioritized as we age.
Can You Stack Muscle Builders?
Most of the best supplements for muscle growth can be stacked or combined for even better results. Stacking different supplements can help you customize supplementation to your specific goals. However, do your research first, and always take the best gym supplements as directed to avoid any adverse effects.
What Increases Muscle Size Fast?
A combination of weight training, a strict diet, and any of the best supplements for muscle growth on our list can help you develop muscle quickly. Understanding the individual needs of the human body will help you tailor your program to maximize results.
How Can I Bulk in 7 Days?
Gaining significant, quality muscle mass in just 7 days isn't realistic, as the process takes consistent effort over weeks and months. However, you can maximize muscle fullness and see a noticeable jump on the scale within a week. To do that, increase your calorie intake, stay well-hydrated, continue intense weight training, and add any of the best legal supplements for muscle growth (like creatine) to your routine.
What Is the Best Protein Powder for Muscle Gain?
The ideal choice depends on your needs, budget, taste preferences, and dietary restrictions. However, brands like Kion Clean Protein stand out as one of the best protein supplements for muscle gain. Kion offers some of the best gym supplements known for transparency and effectiveness.
Best Supplements for Muscle Growth: Final Thoughts
Muscle growth is a process that requires dedication and commitment. The best supplements for muscle growth can help you reach your goals by increasing protein synthesis and aiding muscle repair.
The products on our list are all effective for muscle growth and are backed by science. We recommend PrimeShred as the best overall supplement for muscle growth because it's effective and affordable.
However, Testogen is also an excellent choice for those looking for a natural supplement to boost testosterone levels with their fitness routine.
Whatever product you choose, follow the instructions on how to take it and pair it with a healthy diet and exercise program for the best results.
References
- “Check out this Amazon Review of PrimeShred: Fat Burner for Men, Natural Appetite Suppressant, Thermogenic Workout Metabolism Booster & Energy Supplement, Weight Management w/Green Tea, Caffeine L-Carnitine, Vegan & Soy-Free, 90 Caps.” Amazon.com, https://www.amazon.com/gp/aw/review/B0BX3Q3MTM/R1HKWA34WJLLCP. Accessed 6 Apr. 2025.
- “Check out this Amazon Review of PrimeShred: Fat Burner for Men, Natural Appetite Suppressant, Thermogenic Workout Metabolism Booster & Energy Supplement, Weight Management w/Green Tea, Caffeine L-Carnitine, Vegan & Soy-Free, 90 Caps.” Amazon.com, https://www.amazon.com/gp/aw/review/B0BX3Q3MTM/R9ROM7FP76R3W. Accessed 6 Apr. 2025.
- “Check out This Amazon Review of TestoGen Booster for Men - Natural Male Vitality Supplement to Combat Low Energy Levels, Fight Fatigue, Support Weight Control, Muscle Growth & Focus - 3-Month Supply.” Amazon.com, https://www.amazon.com/gp/aw/review/B09BK2TPHC/R362WG47HL236G. Accessed 6 Apr. 2025.
- “Check out This Amazon Review of TestoGen Booster for Men - Natural Male Vitality Supplement to Combat Low Energy Levels, Fight Fatigue, Support Weight Control, Muscle Growth & Focus - 3-Month Supply.” Amazon.com, https://www.amazon.com/gp/aw/review/B09BK2TPHC/R2HWVWBVOD462H. Accessed 6 Apr. 2025.
- “Jonathan Swan Gave TestoPrime 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/67d3fe2706ad6a9504ea8c68. Accessed 6 Apr. 2025.
- “Ayman N Gave TestoPrime 2 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/67b2c50c08a7dc9b0a9dbd8f. Accessed 6 Apr. 2025.
- “Jason Paxton Gave CrazyBulk 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/66b81e3e21f58f9057e15388. Accessed 6 Apr. 2025.
- “Sam Jar Gong Jarmin Gave CrazyBulk 2 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/66b7b6abd00030f57845f74f. Accessed 6 Apr. 2025.
- “Edward Sokoloski Gave CrazyBulk 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/605d4a6df85d750870358caf. Accessed 6 Apr. 2025.
- “John DAlexander Gave CrazyBulk 1 Star. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/62253840361b35c36d5f293d. Accessed 6 Apr. 2025.
- “Ramiro Gonzalez Gave CrazyBulk 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/6440507f746ca7dfea0cd68f. Accessed 6 Apr. 2025.
- “Jeff Bivens Gave CrazyBulk 1 Star. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/66be64bb9c884dc44899972f. Accessed 6 Apr. 2025.
- “Jason Hooper Gave CrazyBulk 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/5fff1a51755dc10ab819155d. Accessed 6 Apr. 2025.
- “Jimmy Ramirez Gave CrazyBulk 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/62ff97f0142fce1f45fed78b. Accessed 6 Apr. 2025.
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